Specialty Compounds

5-Amino-1MQ

Name: 5-Amino-1MQ
Brand: Vortex Research
SKU: VR-21110
Price: 54.99 USD
Availability: InStock

5-Amino-1MQ 50 mg (5-amino-1-methylquinolinium) is a quaternary quinolinium small molecule, not a peptide, supplied as a research compound; the published lot report shows 99.97% HPLC purity.

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99.97% HPLC purity · Lot report published

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CHEMICAL BLOCK

The data your lab notebook needs.

Identity data for this material. Published lot reports, where one exists, are in the lab report library.

FORM	Lyophilized Powder
PURITY	Per lot (see published lab report)
STORAGE	Lyophilized (powder): −20°C, away from light, unopened

COMMON QUESTIONS

Everything researchers ask before ordering.

No. 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule: a quinoline ring N-methylated at position one with an amino group at position five. Because the cation is permanently charged, it is supplied as a salt, most often the iodide (C10H11IN2, about 286.1 g/mol, CAS 42464-96-0).

ILS Laboratories tested lot PS07-5AM50 on 08/12/2026. The report shows 99.97% purity by HPLC, identity by HPLC, 51.54 mg net content against the 50 mg label, and results for heavy metals (ICP-MS), sterility (PCR), endotoxin (USP 85) and a fentanyl screen.

This certificate was issued by ILS Laboratories to our wholesale partner facility. Vortex stocks the same batch, so the report covers the lot we ship. Vortex-name testing is in progress and will replace it on the COA page when it is issued.

Look the report up on the ILS portal, portal.ils-lab.com, with access code TKZJPXTW (COA number COA-2026-PYEP3A).

Orders placed before 2pm EST ship same day. Standard ground delivery takes 2–4 business days within the continental US. Expedited options are available at checkout.

Each order includes the research material. Where a report is published for the stocked lot, it is linked on this page and listed at vortexresearch.net/coa/.

Tested lots are reported by independent labs (ILS Laboratories and Freedom Diagnostics). Each published report names the lab, the lot, the test date and every assay run, including purity by HPLC and identity by HPLC or LC-MS. All reports are listed at vortexresearch.net/coa/.

Store lyophilized powder at −20°C, away from light, until use.

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All sales are final. If your order arrives damaged or incorrect, contact us within 7 days of delivery and we'll make it right.

No. All products sold by Vortex Research are designated for in vitro laboratory research use only by qualified professionals. They are not approved for human or veterinary use.

Additional information

Mass	50MG

Compound information

5-Amino-1MQ research data.

5-Amino-1-methylquinolinium, a quaternary quinolinium small molecule (not a peptide)

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule, not a peptide. It is a quaternary quinolinium cation: a quinoline ring N-methylated at position one and carrying an amino group at position five. Because it is a permanently charged cation, it is supplied as a salt, most often the iodide. It came out of a 2017 medicinal-chemistry series of quinolinium compounds made at the University of Texas Medical Branch.

The compound sits in the literature on small-molecule inhibitors of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide. Published work spans structure-activity studies in enzyme assays, a validated LC-MS/MS bioanalytical method with rat pharmacokinetic data, and reviews of NNMT inhibitor chemistry. The references below are limited to these chemistry and analytical papers.

Type	Small molecule, quaternary quinolinium cation (not a peptide)
Also listed as	5-amino-1-methylquinolinium, 5-AMQ
IUPAC name	1-methylquinolin-1-ium-5-amine
Formula	C10H11N2+ (cation); C10H11IN2 (iodide salt)
Molecular weight	~159.2 g/mol (cation); ~286.1 g/mol (iodide salt)
CAS	685079-15-6 (cation); 42464-96-0 (iodide salt)
PubChem CID	950107 (cation); 66522933 (iodide salt)

Lab reports

Lot reports for this product.

Each report names the lab, the lot, the test date and every assay run. Verify it on the lab's own portal.

50 mg · Lot PS07-5AM5099.97% purity (HPLC)

Lab	ILS Laboratories, San Diego, CA
Report type	Partner-facility report on the same batch Vortex stocks
Tested	08/12/2026
Net content	51.54 mg
COA number	COA-2026-PYEP3A
Access code	TKZJPXTW

Assays: Purity (HPLC), Identity (HPLC), Net content, Heavy metals (ICP-MS), Sterility (PCR), Endotoxin (USP <85>), Fentanyl screen

Verify at the lab →

All published reports: lab report library →

Sources & references

Published literature.

Peer-reviewed papers on 5-Amino-1MQ, linked to PubMed.

Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase.
Neelakantan H, Wang HY, Vance V, et al.. J Med Chem (2017). PubMed 28548833 →
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies.
Awosemo O, Neelakantan H, Watowich S, et al.. J Pharm Biomed Anal (2021). PubMed 34304009 →
Mechanisms and inhibitors of nicotinamide N-methyltransferase.
Iyamu ID, Huang R. RSC Med Chem (2021). PubMed 34458733 →

For in-vitro laboratory research use only by qualified researchers. Not for human or veterinary consumption. Not a drug, dietary supplement or cosmetic. These statements have not been evaluated by the FDA, and this product is not intended to diagnose, treat, cure or prevent any disease. This site does not provide medical advice. Literature listed above describes published research and is not a claim about this product. By purchasing, the buyer confirms the material is for laboratory research conducted by qualified personnel.

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